Version 5.4
Mus musculus Gene: Htr7
Summary
InnateDB Gene IDBG-160393.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Htr7
Gene Name 5-hydroxytryptamine (serotonin) receptor 7
Synonyms 5-HT7
Species Mus musculus
Ensembl Gene ENSMUSG00000024798
Encoded Proteins
IDBP-160397
5-hydroxytryptamine (serotonin) receptor 7
IDBP-621223
5-hydroxytryptamine (serotonin) receptor 7
IDBP-621224
5-hydroxytryptamine (serotonin) receptor 7
IDBP-621226
5-hydroxytryptamine (serotonin) receptor 7
IDBP-621228
5-hydroxytryptamine (serotonin) receptor 7
IDBP-621233
5-hydroxytryptamine (serotonin) receptor 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148680:
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35958734-36057507
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000099505 ENSMUSP00000097105
ENSMUST00000164639 ENSMUSP00000126847
ENSMUST00000165215 ENSMUSP00000128386
ENSMUST00000164781 ENSMUSP00000131912
ENSMUST00000166074 ENSMUSP00000126150
ENSMUST00000170360 ENSMUSP00000131517
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004993 serotonin receptor activity
Biological Process
GO:0006939 smooth muscle contraction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007210 serotonin receptor signaling pathway
GO:0007268 synaptic transmission
GO:0007623 circadian rhythm
GO:0042310 vasoconstriction
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000148680
View Gene Order
ENSBTAG00000008783
Not yet available
Pathways
NETPATH
REACTOME
REACT_242871
G alpha (s) signalling events pathway
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_252999
Amine ligand-binding receptors pathway
REACT_232980
Serotonin receptors pathway
REACT_231468
GPCR ligand binding pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04020
Calcium signaling pathway pathway
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19327
G alpha (s) signalling events pathway
REACT_17064
Serotonin receptors pathway
REACT_16983
Amine ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
hsa04020
Calcium signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9Q4Q7
UniProt Splice Variant
Entrez Gene 15566
UniGene Mm.254266
RefSeq NM_008315 XM_006526702
OMIM
CCDS CCDS29769
HPRD
IMGT
MGI ID MGI:99841
MGI Symbol Htr7
EMBL AC133874
GenPept
RNA Seq Atlas 15566

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca