Version 5.4
Mus musculus Gene: Cpeb2
Summary
InnateDB Gene IDBG-160824.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cpeb2
Gene Name cytoplasmic polyadenylation element binding protein 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039782
Encoded Proteins
IDBP-252556
cytoplasmic polyadenylation element binding protein 2
IDBP-252558
cytoplasmic polyadenylation element binding protein 2
IDBP-627730
cytoplasmic polyadenylation element binding protein 2
IDBP-627731
cytoplasmic polyadenylation element binding protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137449:
The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:43233463-43289724
Strand Forward strand
Band B3
Transcripts
ENSMUST00000114066 ENSMUSP00000109700
ENSMUST00000114065 ENSMUSP00000109699
ENSMUST00000127599
ENSMUST00000166713 ENSMUSP00000130921
ENSMUST00000169035 ENSMUSP00000125857
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000900 translation repressor activity, nucleic acid binding
GO:0003676 nucleic acid binding
GO:0005095 GTPase inhibitor activity
GO:0005515 protein binding
GO:0008187 poly-pyrimidine tract binding
GO:0035925 mRNA 3'-UTR AU-rich region binding
GO:0043022 ribosome binding
GO:0043023 ribosomal large subunit binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0032869 cellular response to insulin stimulus
GO:0033125 negative regulation of GTP catabolic process
GO:0034260 negative regulation of GTPase activity
GO:0034599 cellular response to oxidative stress
GO:0045900 negative regulation of translational elongation
GO:0071243 cellular response to arsenic-containing substance
GO:0071456 cellular response to hypoxia
GO:1900248 negative regulation of cytoplasmic translational elongation
GO:2000766 negative regulation of cytoplasmic translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005844 polysome
GO:1990124 messenger ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000137449
View Gene Order
ENSBTAG00000019847
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04320
Dorso-ventral axis formation pathway
mmu04914
Progesterone-mediated oocyte maturation pathway
mmu04114
Oocyte meiosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04320
Dorso-ventral axis formation pathway
hsa04914
Progesterone-mediated oocyte maturation pathway
hsa04114
Oocyte meiosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.398905 Mm.408452 Mm.7233
RefSeq NM_001177379 NM_175937 XM_006503929 XM_006503930
OMIM
CCDS CCDS51487
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca