Version 5.4
Mus musculus Gene: Kif11
Summary
InnateDB Gene IDBG-161597.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kif11
Gene Name kinesin family member 11
Synonyms Eg5; Kif8; Kifl1; Knsl1
Species Mus musculus
Ensembl Gene ENSMUSG00000012443
Encoded Proteins
IDBP-161599
kinesin family member 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138160:
This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:37376403-37421859
Strand Forward strand
Band C2
Transcripts
ENSMUST00000012587 ENSMUSP00000012587
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0019901 protein kinase binding
GO:0032403 protein complex binding
Biological Process
GO:0007018 microtubule-based movement
GO:0007051 spindle organization
GO:0007100 mitotic centrosome separation
GO:0008152 metabolic process
GO:0090307 spindle assembly involved in mitosis
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0005876 spindle microtubule
GO:0016020 membrane
GO:0072686 mitotic spindle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138160
View Gene Order
ENSBTAG00000009383
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_230745
Immune System pathway
REACT_199117
Kinesins pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121399
MHC class II antigen presentation pathway
REACT_25201
Kinesins pathway
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.412502 Mm.415819 Mm.42203
RefSeq NM_010615
OMIM
CCDS CCDS29777
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca