Mus musculus Gene: Ctsl
Summary
InnateDB Gene IDBG-161957.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ctsl
Gene Name cathepsin L
Synonyms 1190035F06Rik; Ctsl1; fs; MEP; nkt
Species Mus musculus
Ensembl Gene ENSMUSG00000021477
Encoded Proteins
cathepsin L
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:64363214-64370306
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000021933 ENSMUSP00000021933
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004177 aminopeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0005515 protein binding
GO:0008234 cysteine-type peptidase activity
GO:0016807 cysteine-type carboxypeptidase activity
GO:0030984 kininogen binding
GO:0032403 protein complex binding
GO:0042277 peptide binding
GO:0042393 histone binding
Biological Process
GO:0006508 proteolysis
GO:0007154 cell communication
GO:0007283 spermatogenesis
GO:0008584 male gonad development
GO:0009267 cellular response to starvation
GO:0009749 response to glucose
GO:0010259 multicellular organismal aging
GO:0010839 negative regulation of keratinocyte proliferation
GO:0014070 response to organic cyclic compound
GO:0016485 protein processing
GO:0016540 protein autoprocessing
GO:0021675 nerve development
GO:0031069 hair follicle morphogenesis
GO:0034698 response to gonadotropin
GO:0042637 catagen
GO:0046697 decidualization
GO:0048102 autophagic cell death
GO:0051384 response to glucocorticoid
GO:0060008 Sertoli cell differentiation
GO:2000249 regulation of actin cytoskeleton reorganization
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005773 vacuole
GO:0005902 microvillus
GO:0009897 external side of plasma membrane
GO:0030141 secretory granule
GO:0031410 cytoplasmic vesicle
GO:0043005 neuron projection
GO:0043204 perikaryon
GO:0045177 apical part of cell
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Collagen formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Innate Immune System pathway
Trafficking and processing of endosomal TLR pathway
Activation of Matrix Metalloproteinases pathway
Immune System pathway
Extracellular matrix organization pathway
MHC class II antigen presentation pathway
Toll-Like Receptors Cascades pathway
Adaptive Immune System pathway
Degradation of the extracellular matrix pathway
Collagen degradation pathway
KEGG
Antigen processing and presentation pathway
Lysosome pathway
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.401377 Mm.930
RefSeq NM_009984 XM_006517080 XM_006517081
OMIM
CCDS CCDS26600
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas