Version 5.4
Mus musculus Gene: Igbp1
Summary
InnateDB Gene IDBG-162064.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Igbp1
Gene Name immunoglobulin (CD79A) binding protein 1
Synonyms AI115586; AI662457; AW208785; C81413; p52; Pc52; Tap42
Species Mus musculus
Ensembl Gene ENSMUSG00000031221
Encoded Proteins
IDBP-162066
immunoglobulin (CD79A) binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089289:
The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:100494291-100516125
Strand Forward strand
Band C3
Transcripts
ENSMUST00000033570 ENSMUSP00000033570
ENSMUST00000144881
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 113 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 113 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008601 protein phosphatase type 2A regulator activity
GO:0019904 protein domain specific binding
GO:0031434 mitogen-activated protein kinase kinase binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0009966 regulation of signal transduction
GO:0032873 negative regulation of stress-activated MAPK cascade
GO:0034612 response to tumor necrosis factor
GO:0035306 positive regulation of dephosphorylation
GO:0035308 negative regulation of protein dephosphorylation
GO:0042113 B cell activation
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060632 regulation of microtubule-based movement
GO:0070555 response to interleukin-1
GO:2001234 negative regulation of apoptotic signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000089289
View Gene Order
ENSBTAG00000007797
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_56
Prolactin pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q61249
TrEMBL
UniProt Splice Variant
Entrez Gene 18518
UniGene Mm.482393 Mm.483724 Mm.484804 Mm.7454
RefSeq NM_008784
OMIM
CCDS CCDS30302
HPRD
IMGT
MGI ID MGI:1346500
MGI Symbol Igbp1
EMBL AJ000633 AJ000634 AJ223156 AJ223157 AJ223158 AJ223159 AJ223160 L31652
GenPept AAA67891 CAA04190 CAA04191 CAA11135
RNA Seq Atlas 18518

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca