Version 5.4
Mus musculus Gene: Gtpbp1
Summary
InnateDB Gene IDBG-162385.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gtpbp1
Gene Name GTP binding protein 1
Synonyms AL022987; AW045683; C85212; GP-1; Gtpbp
Species Mus musculus
Ensembl Gene ENSMUSG00000042535
Encoded Proteins
IDBP-162391
GTP binding protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100226:
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:79690895-79721478
Strand Forward strand
Band E1
Transcripts
ENSMUST00000046463 ENSMUSP00000043575
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006184 GTP catabolic process
GO:0061014 positive regulation of mRNA catabolic process
Cellular Component
GO:0000177 cytoplasmic exosome (RNase complex)
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100226
View Gene Order
ENSBTAG00000010324
Not yet available
Cross-References
SwissProt O08582
TrEMBL
UniProt Splice Variant
Entrez Gene 14904
UniGene Mm.19080
RefSeq NM_013818 XM_006520450
OMIM
CCDS CCDS27648
HPRD
IMGT
MGI ID MGI:109443
MGI Symbol Gtpbp1
EMBL AK004612 AK147717 AK150068 AK150185 AK170091 BC046228 U87965
GenPept AAB51274 AAH46228 BAB23409 BAE28091 BAE29280 BAE29365 BAE41557
RNA Seq Atlas 14904

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca