Version 5.4
Homo sapiens Gene: DIRAS1
Summary
InnateDB Gene IDBG-16265.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DIRAS1
Gene Name DIRAS family, GTP-binding RAS-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176490
Encoded Proteins
IDBP-16267
DIRAS family, GTP-binding RAS-like 1
IDBP-761941
IDBP-762815
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:2714567-2721418
Strand Reverse strand
Band p13.3
Transcripts
ENST00000323469 ENSP00000325836
ENST00000585334 ENSP00000468417
ENST00000588128 ENSP00000466733
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043670
View Gene Order
ENSBTAG00000045981
Not yet available
Cross-References
SwissProt
TrEMBL K7EN06
UniProt Splice Variant
Entrez Gene 148252
UniGene Hs.172753 Hs.622677
RefSeq NM_145173
HUGO HGNC:19127
OMIM 607862
CCDS CCDS12092
HPRD 09710
IMGT
EMBL AC006538
GenPept
RNA Seq Atlas 148252

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca