Version 5.4
Mus musculus Gene: Mtap2
Summary
InnateDB Gene IDBG-162983.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtap2
Gene Name microtubule-associated protein 2
Synonyms G1-397-34; MAP-2; Mtap-2; Mtap2; repro4
Species Mus musculus
Ensembl Gene ENSMUSG00000015222
Encoded Proteins
IDBP-162985
microtubule-associated protein 2
IDBP-162987
microtubule-associated protein 2
IDBP-252643
microtubule-associated protein 2
IDBP-252645
microtubule-associated protein 2
IDBP-252647
microtubule-associated protein 2
IDBP-252649
microtubule-associated protein 2
IDBP-252651
microtubule-associated protein 2
IDBP-622260
microtubule-associated protein 2
IDBP-539134
microtubule-associated protein 2
IDBP-539955
microtubule-associated protein 2
IDBP-622292
microtubule-associated protein 2
IDBP-622287
microtubule-associated protein 2
IDBP-622296
microtubule-associated protein 2
IDBP-622297
microtubule-associated protein 2
IDBP-622298
microtubule-associated protein 2
IDBP-622299
microtubule-associated protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000078018:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:66175273-66442583
Strand Forward strand
Band C3
Transcripts
ENSMUST00000024639 ENSMUSP00000024639
ENSMUST00000077355 ENSMUSP00000076577
ENSMUST00000114018 ENSMUSP00000109651
ENSMUST00000114017 ENSMUSP00000109650
ENSMUST00000114015 ENSMUSP00000109648
ENSMUST00000114013 ENSMUSP00000109646
ENSMUST00000114012 ENSMUSP00000109645
ENSMUST00000156636 ENSMUSP00000133871
ENSMUST00000124873
ENSMUST00000125844
ENSMUST00000128673
ENSMUST00000137807
ENSMUST00000123647 ENSMUSP00000119341
ENSMUST00000141148 ENSMUSP00000117996
ENSMUST00000151423
ENSMUST00000145419 ENSMUSP00000134538
ENSMUST00000127388
ENSMUST00000133522
ENSMUST00000173855 ENSMUSP00000134471
ENSMUST00000174590
ENSMUST00000172886 ENSMUSP00000133446
ENSMUST00000173778 ENSMUSP00000134651
ENSMUST00000173800 ENSMUSP00000134518
ENSMUST00000172486 ENSMUSP00000134187
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002162 dystroglycan binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005519 cytoskeletal regulatory protein binding
GO:0008017 microtubule binding
GO:0015631 tubulin binding
Biological Process
GO:0001578 microtubule bundle formation
GO:0007409 axonogenesis
GO:0016358 dendrite development
GO:0021954 central nervous system neuron development
GO:0031175 neuron projection development
GO:0048813 dendrite morphogenesis
GO:0071310 cellular response to organic substance
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0030425 dendrite
GO:0034399 nuclear periphery
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043198 dendritic shaft
GO:0044297 cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000078018
View Gene Order
ENSBTAG00000018130
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
lkb1_pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.256966 Mm.396589 Mm.410631 Mm.487809
RefSeq NM_001039934 NM_008632 XM_006495747 XM_006495754 XM_006495755 XM_006495756 XM_006495757 XM_006495759 XM_006495760 XM_006495761 XM_006495762 XM_006536910 XM_006536911 XM_006536912
OMIM
CCDS CCDS15020 CCDS35602
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca