InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cct7

Summary

InnateDB Gene

IDBG-163557.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cct7

Gene Name

chaperonin containing Tcp1, subunit 7 (eta)

Synonyms

AA408524; AL022769; Ccth; Cctz

Species

Mus musculus

Ensembl Gene

ENSMUSG00000030007

Encoded Proteins

IDBP-163559

chaperonin containing Tcp1, subunit 7 (eta)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135624:
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:85451505-85468477

Strand

Forward strand

Band

Transcripts

ENSMUST00000032078

ENSMUSP00000032078

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 78 interaction(s) predicted by orthology.

Experimentally validated
Total	19 [view]
Protein-Protein	19 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	78 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0042802	identical protein binding
GO:0051082	unfolded protein binding

Biological Process

GO:0006457	protein folding
GO:0007339	binding of sperm to zona pellucida
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0002199	zona pellucida receptor complex
GO:0005739	mitochondrion
GO:0005832	chaperonin-containing T-complex
GO:0005874	microtubule
GO:0044297	cell body
GO:0070062	extracellular vesicular exosome