Version 5.4
Mus musculus Gene: Cacna1i
Summary
InnateDB Gene IDBG-163676.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cacna1i
Gene Name calcium channel, voltage-dependent, alpha 1I subunit
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022416
Encoded Proteins
IDBP-536779
calcium channel, voltage-dependent, alpha 1I subunit
IDBP-532287
calcium channel, voltage-dependent, alpha 1I subunit
IDBP-533540
calcium channel, voltage-dependent, alpha 1I subunit
IDBP-540052
calcium channel, voltage-dependent, alpha 1I subunit
IDBP-536246
calcium channel, voltage-dependent, alpha 1I subunit
IDBP-531811
calcium channel, voltage-dependent, alpha 1I subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100346:
This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:80287238-80398279
Strand Forward strand
Band E1
Transcripts
ENSMUST00000160424 ENSMUSP00000125063
ENSMUST00000162155 ENSMUSP00000125229
ENSMUST00000160175 ENSMUSP00000123881
ENSMUST00000161863 ENSMUSP00000124367
ENSMUST00000162025 ENSMUSP00000125530
ENSMUST00000162913 ENSMUSP00000125617
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005245 voltage-gated calcium channel activity
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0019228 neuronal action potential
GO:0030431 sleep
GO:0034765 regulation of ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070509 calcium ion import
GO:0086010 membrane depolarization during action potential
Cellular Component
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100346
View Gene Order
ENSBTAG00000045610
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04020
Calcium signaling pathway pathway
mmu04010
MAPK signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18312
NCAM1 interactions pathway
REACT_18334
NCAM signaling for neurite out-growth pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
KEGG
hsa04010
MAPK signaling pathway pathway
hsa04020
Calcium signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9Q7P2 Q99M83
UniProt Splice Variant
Entrez Gene 239556
UniGene Mm.291058
RefSeq NM_001044308
OMIM
CCDS CCDS49670
HPRD
IMGT
MGI ID MGI:2178051
MGI Symbol Cacna1i
EMBL AC155313 AY026384
GenPept AAK21606
RNA Seq Atlas 239556

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca