Version 5.4
Mus musculus Gene: Lancl1
Summary
InnateDB Gene IDBG-163777.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lancl1
Gene Name LanC (bacterial lantibiotic synthetase component C)-like 1
Synonyms AW124738; Gpr69; Gpr69a; p40
Species Mus musculus
Ensembl Gene ENSMUSG00000026000
Encoded Proteins
IDBP-163779
LanC (bacterial lantibiotic synthetase component C)-like 1
IDBP-252736
LanC (bacterial lantibiotic synthetase component C)-like 1
IDBP-401156
LanC (bacterial lantibiotic synthetase component C)-like 1
IDBP-534969
LanC (bacterial lantibiotic synthetase component C)-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115365:
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:67000517-67038872
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000027149 ENSMUSP00000027149
ENSMUST00000113979 ENSMUSP00000109612
ENSMUST00000119559 ENSMUSP00000113080
ENSMUST00000133508
ENSMUST00000149996 ENSMUSP00000122752
ENSMUST00000189210
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017124 SH3 domain binding
GO:0043295 glutathione binding
GO:0050750 low-density lipoprotein particle receptor binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000115365
View Gene Order
ENSBTAG00000015066
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.20522
RefSeq NM_001190984 NM_001190985 NM_021295 XM_006536908
OMIM
CCDS CCDS15025
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca