Version 5.4
Mus musculus Gene: Tctn3
Summary
InnateDB Gene IDBG-164998.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tctn3
Gene Name tectonic family member 3
Synonyms 4930521E07Rik; AI197391; Tect3
Species Mus musculus
Ensembl Gene ENSMUSG00000025008
Encoded Proteins
IDBP-165000
tectonic family member 3
IDBP-541238
tectonic family member 3
IDBP-531873
tectonic family member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119977:
This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:40596446-40612233
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000025981 ENSMUSP00000025981
ENSMUST00000135795 ENSMUSP00000123461
ENSMUST00000132452 ENSMUSP00000121760
ENSMUST00000144566
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0007224 smoothened signaling pathway
GO:0060271 cilium morphogenesis
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119977
View Gene Order
ENSBTAG00000011841
Not yet available
Cross-References
SwissProt Q8R2Q6
TrEMBL
UniProt Splice Variant
Entrez Gene 67590
UniGene
RefSeq NM_026260
OMIM
CCDS CCDS29804
HPRD
IMGT
MGI ID MGI:1914840
MGI Symbol Tctn3
EMBL AK015861 AK016982 AK030156 BC027335 BC080805 DQ278871
GenPept AAH27335 AAH80805 ABB90563 BAB30004 BAB30537 BAC26813
RNA Seq Atlas 67590

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca