InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ift57

Summary

InnateDB Gene

IDBG-165056.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ift57

Gene Name

intraflagellar transport 57

Synonyms

4833420A15Rik; Esrrbl1; Hippi; MHS4R2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000032965

Encoded Proteins

IDBP-165058

intraflagellar transport 57 homolog (Chlamydomonas)

IDBP-533449

intraflagellar transport 57 homolog (Chlamydomonas)

IDBP-532696

intraflagellar transport 57 homolog (Chlamydomonas)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114446:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:49699233-49765126

Strand

Forward strand

Band

Transcripts

ENSMUST00000046777	ENSMUSP00000046645
ENSMUST00000142682	ENSMUSP00000117882
ENSMUST00000127784
ENSMUST00000140914	ENSMUSP00000116412

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding

Biological Process

GO:0001843	neural tube closure
GO:0001947	heart looping
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007224	smoothened signaling pathway
GO:0016192	vesicle-mediated transport
GO:0042073	intraciliary transport
GO:0042981	regulation of apoptotic process
GO:0050680	negative regulation of epithelial cell proliferation
GO:0060271	cilium morphogenesis
GO:0060972	left/right pattern formation

Cellular Component

GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005929	cilium
GO:0016020	membrane
GO:0030992	intraciliary transport particle B
GO:0032391	photoreceptor connecting cilium
GO:0036064	ciliary basal body
GO:0044292	dendrite terminus
GO:0072372	primary cilium