Version 5.4
Mus musculus Gene: Crb2
Summary
InnateDB Gene IDBG-166560.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crb2
Gene Name crumbs homolog 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035403
Encoded Proteins
IDBP-166562
crumbs homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148204:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:37776249-37799103
Strand Forward strand
Band B
Transcripts
ENSMUST00000050372 ENSMUSP00000058007
ENSMUST00000147600
ENSMUST00000137693
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0019828 aspartic-type endopeptidase inhibitor activity
GO:0019899 enzyme binding
Biological Process
GO:0001707 mesoderm formation
GO:0001756 somitogenesis
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0010951 negative regulation of endopeptidase activity
GO:0014028 notochord formation
GO:0030513 positive regulation of BMP signaling pathway
GO:0045199 maintenance of epithelial cell apical/basal polarity
GO:0050896 response to stimulus
GO:0072358 cardiovascular system development
Cellular Component
GO:0016021 integral component of membrane
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000148204
View Gene Order
ENSBTAG00000014391
Not yet available
Cross-References
SwissProt Q80YA8
TrEMBL
UniProt Splice Variant
Entrez Gene 241324
UniGene Mm.392369 Mm.409234
RefSeq NM_001163566
OMIM
CCDS CCDS50580
HPRD
IMGT
MGI ID MGI:2679260
MGI Symbol Crb2
EMBL AL805959 BC043114 BC062128
GenPept AAH43114 AAH62128 CAM22965
RNA Seq Atlas 241324

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca