Mus musculus Gene: Pgm2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-166725.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Pgm2 | ||||||||||||||||||||||
Gene Name | phosphoglucomutase 2 | ||||||||||||||||||||||
Synonyms | 2610020G18Rik; AA407108; AI098105; Pgm-2; Pgm1 | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000025791 | ||||||||||||||||||||||
Encoded Proteins |
phosphoglucomutase 2
phosphoglucomutase 2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000079739:
The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010] The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90%% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 4:99929414-99987294 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | C6 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Disease pathway
Galactose catabolism pathway
Glucose metabolism pathway
Metabolism pathway
Glycogen synthesis pathway
Glycogen breakdown (glycogenolysis) pathway
Glycogen storage diseases pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
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KEGG |
Pentose phosphate pathway pathway
Amino sugar and nucleotide sugar metabolism pathway
Glycolysis / Gluconeogenesis pathway
Starch and sucrose metabolism pathway
Galactose metabolism pathway
Purine metabolism pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TCR pathway
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REACTOME |
Glycogen breakdown (glycogenolysis) pathway
Galactose catabolism pathway
Myoclonic epilepsy of Lafora pathway
Glycogen synthesis pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glucose metabolism pathway
Glycogen storage diseases pathway
Glycogen synthesis pathway
Metabolism of carbohydrates pathway
Myoclonic epilepsy of Lafora pathway
Glycogen storage diseases pathway
Glycogen breakdown (glycogenolysis) pathway
Glucose metabolism pathway
Metabolism pathway
Galactose catabolism pathway
Disease pathway
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KEGG |
Galactose metabolism pathway
Glycolysis / Gluconeogenesis pathway
Amino sugar and nucleotide sugar metabolism pathway
Pentose phosphate pathway pathway
Purine metabolism pathway
Starch and sucrose metabolism pathway
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INOH |
Glycolysis Gluconeogenesis pathway
Pentose phosphate cycle pathway
Galactose metabolism pathway
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PID NCI |
HIF-1-alpha transcription factor network
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Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Mm.412485 | ||||||||||||||||||||||
RefSeq | NM_028132 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS18388 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||