InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Taf9b

Summary

InnateDB Gene

IDBG-167034.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Taf9b

Gene Name

TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000047242

Encoded Proteins

IDBP-167036

TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor

IDBP-253759

TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor

IDBP-541654

TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187325:
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:106206883-106221158

Strand

Reverse strand

Band

Transcripts

ENSMUST00000055497	ENSMUSP00000059751
ENSMUST00000113495	ENSMUSP00000109123
ENSMUST00000134547	ENSMUSP00000115178

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006352	DNA-templated transcription, initiation
GO:0006355	regulation of transcription, DNA-templated
GO:0012501	programmed cell death
GO:0014070	response to organic cyclic compound
GO:0030307	positive regulation of cell growth
GO:0043066	negative regulation of apoptotic process
GO:0050821	protein stabilization