Version 5.4
Mus musculus Gene: Hnrnpm
Summary
InnateDB Gene IDBG-167580.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hnrnpm
Gene Name heterogeneous nuclear ribonucleoprotein M
Synonyms 2610023M21Rik; AA409009; Hnrpm; mKIAA4193
Species Mus musculus
Ensembl Gene ENSMUSG00000059208
Encoded Proteins
IDBP-167582
heterogeneous nuclear ribonucleoprotein M
IDBP-251872
heterogeneous nuclear ribonucleoprotein M
IDBP-533001
heterogeneous nuclear ribonucleoprotein M
IDBP-536764
heterogeneous nuclear ribonucleoprotein M
IDBP-542396
heterogeneous nuclear ribonucleoprotein M
IDBP-535514
heterogeneous nuclear ribonucleoprotein M
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000099783:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:33646233-33686860
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000087582 ENSMUSP00000084864
ENSMUST00000114385 ENSMUSP00000110027
ENSMUST00000148178 ENSMUSP00000120115
ENSMUST00000139302 ENSMUSP00000115787
ENSMUST00000130946 ENSMUSP00000116671
ENSMUST00000148258 ENSMUSP00000123580
ENSMUST00000153608
ENSMUST00000127598
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 181 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 181 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0016020 membrane
GO:0016363 nuclear matrix
GO:0042382 paraspeckles
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000099783
View Gene Order
ENSBTAG00000021039
Not yet available
Pathways
NETPATH
REACTOME
REACT_249110
mRNA Splicing pathway
REACT_233572
Gene Expression pathway
REACT_260226
mRNA Splicing - Major Pathway pathway
REACT_233950
Processing of Capped Intron-Containing Pre-mRNA pathway
KEGG
mmu03040
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.311439 Mm.399541
RefSeq NM_001109913 NM_029804
OMIM
CCDS CCDS37570 CCDS50068
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca