Version 5.4
Mus musculus Gene: A4galt
Summary
InnateDB Gene IDBG-168008.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol A4galt
Gene Name alpha 1,4-galactosyltransferase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000047878
Encoded Proteins
IDBP-168010
alpha 1,4-galactosyltransferase
IDBP-623357
alpha 1,4-galactosyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:83226726-83251774
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000049530 ENSMUSP00000057999
ENSMUST00000164614 ENSMUSP00000129719
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008378 galactosyltransferase activity
GO:0015643 toxic substance binding
GO:0050512 lactosylceramide 4-alpha-galactosyltransferase activity
Biological Process
GO:0001576 globoside biosynthetic process
GO:0006486 protein glycosylation
GO:0007009 plasma membrane organization
Cellular Component
GO:0000139 Golgi membrane
GO:0005795 Golgi stack
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128274
View Gene Order
ENSBTAG00000026497
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00603
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00603
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.323805
RefSeq NM_001004150 NM_001170954
OMIM
CCDS CCDS27699
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca