Version 5.4
Mus musculus Gene: Rcn2
Summary
InnateDB Gene IDBG-168462.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rcn2
Gene Name reticulocalbin 2
Synonyms AA408742; Tcbp49
Species Mus musculus
Ensembl Gene ENSMUSG00000032320
Encoded Proteins
IDBP-252119
reticulocalbin 2
IDBP-531750
reticulocalbin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117906:
The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:56041845-56061882
Strand Forward strand
Band B
Transcripts
ENSMUST00000114276 ENSMUSP00000109915
ENSMUST00000147842 ENSMUSP00000120953
ENSMUST00000151585
ENSMUST00000144869
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000117906
View Gene Order
ENSBTAG00000015780
Not yet available
Cross-References
SwissProt Q8BP92
TrEMBL Q3TE95
UniProt Splice Variant
Entrez Gene 26611
UniGene Mm.1782 Mm.402664
RefSeq NM_011992
OMIM
CCDS CCDS23206
HPRD
IMGT
MGI ID MGI:1349765
MGI Symbol Rcn2
EMBL AF049125 AK077486 AK169765 BC132320 BC145668
GenPept AAC05132 AAI32321 AAI45669 BAC36825 BAE41353
RNA Seq Atlas 26611

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca