Version 5.4
Homo sapiens Gene: NDUFB1
Summary
InnateDB Gene IDBG-16853.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDUFB1
Gene Name NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
Synonyms CI-MNLL; CI-SGDH; MNLL
Species Homo sapiens
Ensembl Gene ENSG00000183648
Encoded Proteins
IDBP-16855
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
IDBP-595777
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
IDBP-593139
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
IDBP-810488
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
IDBP-810490
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:92116122-92121917
Strand Reverse strand
Band q32.12
Transcripts
ENST00000329559 ENSP00000330787
ENST00000553514 ENSP00000451090
ENST00000553666
ENST00000555441 ENSP00000450776
ENST00000556555
ENST00000605997 ENSP00000475170
ENST00000617122 ENSP00000483888
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_004545
HUGO
OMIM
CCDS CCDS9901
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca