Mus musculus Gene: Ivl
Summary
InnateDB Gene IDBG-168702.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ivl
Gene Name involucrin
Synonyms 1110019C06Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000049128
Encoded Proteins
involucrin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163207:
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:92570912-92573715
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000053107 ENSMUSP00000059780
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0030674 protein binding, bridging
Biological Process
GO:0010224 response to UV-B
GO:0018149 peptide cross-linking
GO:0030216 keratinocyte differentiation
GO:0031424 keratinization
Cellular Component
GO:0001533 cornified envelope
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Cross-References
SwissProt
TrEMBL A7MCU8 G3X9D9 Q9EQ57 Q9ERR3 Q9ERR4
UniProt Splice Variant
Entrez Gene 16447
UniGene Mm.207365
RefSeq NM_008412 XM_006501046 XM_006501047
OMIM
CCDS CCDS17561
HPRD
IMGT
MGI ID MGI:96626
MGI Symbol Ivl
EMBL AC125089 AF289925 AF289927 AF290953 BC152326 CH466656
GenPept AAG33372 AAG33374 AAG34655 AAI52327 EDL00692
RNA Seq Atlas 16447