InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Col8a1

Summary

InnateDB Gene

IDBG-168817.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col8a1

Gene Name

collagen, type VIII, alpha 1

Synonyms

Col8a-1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000068196

Encoded Proteins

IDBP-168819

collagen, type VIII, alpha 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144810:
This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:57624258-57754737

Strand

Reverse strand

Band

C1.1

Transcripts

ENSMUST00000089332

ENSMUSP00000086745

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001525	angiogenesis
GO:0007155	cell adhesion
GO:0010811	positive regulation of cell-substrate adhesion
GO:0048593	camera-type eye morphogenesis
GO:0050673	epithelial cell proliferation

Cellular Component

GO:0005581	collagen trimer
GO:0005604	basement membrane
GO:0031012	extracellular matrix
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome