Version 5.4
| Mus musculus Gene: Nup50 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-170060.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | Nup50 | ||||||||||||||||||||||
| Gene Name | nucleoporin 50 | ||||||||||||||||||||||
| Synonyms | 1700030K07Rik; AI413123; Npap60 | ||||||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||||||
| Ensembl Gene | ENSMUSG00000016619 | ||||||||||||||||||||||
| Encoded Proteins |
nucleoporin 50
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| Protein Structure | |||||||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000093000:
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 15:84923428-84942955 | ||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||
| Band | E2 | ||||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
Nuclear Envelope Breakdown pathway
Cell Cycle, Mitotic pathway
Disease pathway
Nuclear Pore Complex (NPC) Disassembly pathway
SLC-mediated transmembrane transport pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
Cell Cycle pathway
Metabolism pathway
M Phase pathway
Transcriptional regulation by small RNAs pathway
Glucose transport pathway
Transmembrane transport of small molecules pathway
Hexose transport pathway
Glycogen storage diseases pathway
Gene Expression pathway
Regulatory RNA pathways pathway
Mitotic Prophase pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
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| KEGG |
RNA transport pathway
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| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||
| REACTOME |
ISG15 antiviral mechanism pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
Glucose transport pathway
Hexose transport pathway
Nuclear import of Rev protein pathway
Vpr-mediated nuclear import of PICs pathway
Rev-mediated nuclear export of HIV RNA pathway
Viral Messenger RNA Synthesis pathway
Late Phase of HIV Life Cycle pathway
Transmembrane transport of small molecules pathway
Influenza Infection pathway
Interactions of Vpr with host cellular proteins pathway
Myoclonic epilepsy of Lafora pathway
Antiviral mechanism by IFN-stimulated genes pathway
Cytokine Signaling in Immune system pathway
Metabolism of carbohydrates pathway
Transcriptional regulation by small RNAs pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Influenza Viral RNA Transcription and Replication pathway
Interferon Signaling pathway
Cell Cycle pathway
Immune System pathway
M Phase pathway
HIV Life Cycle pathway
Mitotic Prophase pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
Influenza Life Cycle pathway
Metabolism pathway
Host Interactions of HIV factors pathway
SLC-mediated transmembrane transport pathway
Interactions of Rev with host cellular proteins pathway
Gene Expression pathway
Nuclear Envelope Breakdown pathway
Disease pathway
Glycogen storage diseases pathway
Regulatory RNA pathways pathway
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| KEGG |
RNA transport pathway
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| INOH | |||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||
| Cross-References | |||||||||||||||||||||||
| SwissProt | |||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| UniGene | Mm.28379 Mm.409546 Mm.457709 | ||||||||||||||||||||||
| RefSeq | NM_016714 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS27714 | ||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| MGI ID | |||||||||||||||||||||||
| MGI Symbol | |||||||||||||||||||||||
| EMBL | |||||||||||||||||||||||
| GenPept | |||||||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||||||