Version 5.4
Mus musculus Gene: Hnrnpab
Summary
InnateDB Gene IDBG-170113.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hnrnpab
Gene Name heterogeneous nuclear ribonucleoprotein A/B
Synonyms 3010025C11Rik; CBF-A; Cgbfa; Hnrpab
Species Mus musculus
Ensembl Gene ENSMUSG00000020358
Encoded Proteins
IDBP-170115
heterogeneous nuclear ribonucleoprotein A/B
IDBP-170117
heterogeneous nuclear ribonucleoprotein A/B
IDBP-263100
heterogeneous nuclear ribonucleoprotein A/B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with consensus RNA binding domains present in a number of other RNA binding proteins and a glycine-rich C-terminus. This gene overlaps in a tail-to-tail orientation the gene encoding alanine-glyoxylate aminotransferase 2-like 2. Some of the exons of this gene are interspersed with exons of alanine-glyoxylate aminotransferase 2-like 2. Two alternatively spliced transcript variants that encode distinct proteins have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:51600100-51606847
Strand Reverse strand
Band B1.3
Transcripts
ENSMUST00000074669 ENSMUSP00000074238
ENSMUST00000101249 ENSMUSP00000098807
ENSMUST00000109103 ENSMUSP00000104731
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 2 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 47 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001837 epithelial to mesenchymal transition
GO:0006351 transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0019013 viral nucleocapsid
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197451
View Gene Order
ENSBTAG00000013627
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.280842
RefSeq NM_001048061 NM_010448
OMIM
CCDS CCDS24654 CCDS48787
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca