Version 5.4
Mus musculus Gene: Scamp5
Summary
InnateDB Gene IDBG-170164.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scamp5
Gene Name secretory carrier membrane protein 5
Synonyms Sc5
Species Mus musculus
Ensembl Gene ENSMUSG00000040722
Encoded Proteins
IDBP-170166
secretory carrier membrane protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 19234194
[Homo sapiens] Promotes calcium-regulated exocytosis of signal peptide-containing cytokine secretion (CCL5 but not IL-1beta) in human monocytes and mouse macrophages
Entrez Gene
Summary This gene encodes a member of the Scamp (secretory carrier membrane protein) family. The encoded protein may be involved in neuronal vesicle trafficking. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:57441328-57468024
Strand Reverse strand
Band B
Transcripts
ENSMUST00000046587 ENSMUSP00000035898
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006887 exocytosis
GO:0015031 protein transport
GO:0034976 response to endoplasmic reticulum stress
GO:0045806 negative regulation of endocytosis
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0050715 positive regulation of cytokine secretion
Cellular Component
GO:0000139 Golgi membrane
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0031201 SNARE complex
GO:0032588 trans-Golgi network membrane
GO:0055038 recycling endosome membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000198794
View Gene Order
ENSBTAG00000021318
Not yet available
Cross-References
SwissProt Q9JKD3
TrEMBL
UniProt Splice Variant
Entrez Gene 56807
UniGene Mm.102278 Mm.401438 Mm.407202
RefSeq NM_020270 XM_006511318 XM_006511319 XM_006511320 XM_006511321
OMIM
CCDS CCDS40649
HPRD
IMGT
MGI ID MGI:1928948
MGI Symbol Scamp5
EMBL AF241833 BC018613
GenPept AAF64491 AAH18613
RNA Seq Atlas 56807

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca