Mus musculus Gene: Tspan6 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-170366.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Tspan6 | ||||||||
Gene Name | tetraspanin 6 | ||||||||
Synonyms | 6720473L21Rik; AI316786; T245; Tm4sf; Tm4sf6; TSPAN-6 | ||||||||
Species | Mus musculus | ||||||||
Ensembl Gene | ENSMUSG00000067377 | ||||||||
Encoded Proteins |
tetraspanin 6
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000000003:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome X:133891068-133898429 | ||||||||
Strand | Reverse strand | ||||||||
Band | E3 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | H3BJJ0 | ||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 56496 | ||||||||
UniGene | Mm.402063 Mm.406163 Mm.46701 | ||||||||
RefSeq | NM_019656 | ||||||||
OMIM | |||||||||
CCDS | CCDS30387 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
MGI ID | MGI:1926264 | ||||||||
MGI Symbol | Tspan6 | ||||||||
EMBL | AL691421 | ||||||||
GenPept | |||||||||
RNA Seq Atlas | 56496 | ||||||||