Version 5.4
Mus musculus Gene: Nupl1
Summary
InnateDB Gene IDBG-170470.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nupl1
Gene Name nucleoporin like 1
Synonyms 1700017F11Rik; mKIAA0410
Species Mus musculus
Ensembl Gene ENSMUSG00000063895
Encoded Proteins
IDBP-170472
nucleoporin like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139496:
This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
This gene encodes a member of the nucleoporin family that shares 87%% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:60219204-60251507
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000041905 ENSMUSP00000038716
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005487 nucleocytoplasmic transporter activity
GO:0005515 protein binding
Biological Process
GO:0006913 nucleocytoplasmic transport
GO:0015031 protein transport
GO:0051028 mRNA transport
Cellular Component
GO:0005643 nuclear pore
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139496
View Gene Order
ENSBTAG00000015225
Not yet available
Pathways
NETPATH
REACTOME
REACT_196648
Nuclear Envelope Breakdown pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_189085
Disease pathway
REACT_196650
Nuclear Pore Complex (NPC) Disassembly pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_204192
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
REACT_188804
Cell Cycle pathway
REACT_188937
Metabolism pathway
REACT_241408
M Phase pathway
REACT_270446
Transcriptional regulation by small RNAs pathway
REACT_253543
Glucose transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_240125
Hexose transport pathway
REACT_203949
Glycogen storage diseases pathway
REACT_233572
Gene Expression pathway
REACT_206535
Regulatory RNA pathways pathway
REACT_250557
Mitotic Prophase pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
mmu03013
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt Q8R332
TrEMBL Q3UZQ6
UniProt Splice Variant
Entrez Gene 71844
UniGene
RefSeq NM_170591
OMIM
CCDS CCDS27175
HPRD
IMGT
MGI ID MGI:1919094
MGI Symbol Nupl1
EMBL AK029688 AK078279 AK086412 AK133721 AK146477 BC026743
GenPept AAH26743 BAC26564 BAC37200 BAC39663 BAE21799 BAE27201
RNA Seq Atlas 71844

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca