Version 5.4
Homo sapiens Gene: ATP8A2
Summary
InnateDB Gene IDBG-17053.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP8A2
Gene Name ATPase, aminophospholipid transporter, class I, type 8A, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132932
Encoded Proteins
IDBP-17055
ATPase, aminophospholipid transporter, class I, type 8A, member 2
IDBP-17059
ATPase, aminophospholipid transporter, class I, type 8A, member 2
IDBP-17061
ATPase, aminophospholipid transporter, class I, type 8A, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:25372071-26025851
Strand Forward strand
Band q12.13
Transcripts
ENST00000281620 ENSP00000281620
ENST00000381655 ENSP00000371070
ENST00000255283 ENSP00000255283
ENST00000381648
ENST00000491840
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005524 ATP binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding
Biological Process
GO:0003011 involuntary skeletal muscle contraction
GO:0006812 cation transport
GO:0007409 axonogenesis
GO:0007568 aging
GO:0008152 metabolic process
GO:0008285 negative regulation of cell proliferation
GO:0010842 retina layer formation
GO:0010976 positive regulation of neuron projection development
GO:0010996 response to auditory stimulus
GO:0015914 phospholipid transport
GO:0031175 neuron projection development
GO:0040018 positive regulation of multicellular organism growth
GO:0042472 inner ear morphogenesis
GO:0042755 eating behavior
GO:0043588 skin development
GO:0045332 phospholipid translocation
GO:0048666 neuron development
GO:0050884 neuromuscular process controlling posture
GO:0050908 detection of light stimulus involved in visual perception
GO:0060052 neurofilament cytoskeleton organization
GO:0061092 positive regulation of phospholipid translocation
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000021983
View Gene Order
Pathways
NETPATH
REACTOME
REACT_25149
Ion transport by P-type ATPases pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.444957 Hs.606154 Hs.608654
RefSeq NM_016529 XM_005266419 XM_006719832 XM_006719833 XM_006719834 XM_006719835 XM_006719836
HUGO
OMIM
CCDS CCDS41873
HPRD 05795
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca