Mus musculus Gene: Cyp1a2
Summary
InnateDB Gene IDBG-170746.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cyp1a2
Gene Name cytochrome P450, family 1, subfamily a, polypeptide 2
Synonyms CP12; Cyp1a1; P450-3
Species Mus musculus
Ensembl Gene ENSMUSG00000032310
Encoded Proteins
cytochrome P450, family 1, subfamily a, polypeptide 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:57676937-57683655
Strand Reverse strand
Band B
Transcripts
ENSMUST00000034860 ENSMUSP00000034860
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0032451 demethylase activity
GO:0034875 caffeine oxidase activity
GO:0070330 aromatase activity
Biological Process
GO:0006706 steroid catabolic process
GO:0006725 cellular aromatic compound metabolic process
GO:0006778 porphyrin-containing compound metabolic process
GO:0009403 toxin biosynthetic process
GO:0009404 toxin metabolic process
GO:0009791 post-embryonic development
GO:0009820 alkaloid metabolic process
GO:0010033 response to organic substance
GO:0010468 regulation of gene expression
GO:0014070 response to organic cyclic compound
GO:0016098 monoterpenoid metabolic process
GO:0017144 drug metabolic process
GO:0018894 dibenzo-p-dioxin metabolic process
GO:0030324 lung development
GO:0032355 response to estradiol
GO:0032496 response to lipopolysaccharide
GO:0032787 monocarboxylic acid metabolic process
GO:0035902 response to immobilization stress
GO:0042493 response to drug
GO:0042737 drug catabolic process
GO:0042738 exogenous drug catabolic process
GO:0045333 cellular respiration
GO:0046483 heterocycle metabolic process
GO:0050665 hydrogen peroxide biosynthetic process
GO:0055114 oxidation-reduction process
GO:0070989 oxidative demethylation
GO:0071276 cellular response to cadmium ion
GO:0071615 oxidative deethylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Cytochrome P450 - arranged by substrate type pathway
Phase 1 - Functionalization of compounds pathway
Aflatoxin activation and detoxification pathway
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 pathway
Phase II conjugation pathway
Metabolism pathway
Methylation pathway
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) pathway
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) pathway
Metabolism of lipids and lipoproteins pathway
Biological oxidations pathway
Xenobiotics pathway
Arachidonic acid metabolism pathway
KEGG
Retinol metabolism pathway
Tryptophan metabolism pathway
Linoleic acid metabolism pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Caffeine metabolism pathway
Steroid hormone biosynthesis pathway
Drug metabolism pathway
INOH
PID NCI
Cross-References
SwissProt P00186
TrEMBL B6VGH4 J3JSM6
UniProt Splice Variant
Entrez Gene 13077
UniGene Mm.15537 Mm.400758
RefSeq NM_009993
OMIM
CCDS CCDS23229
HPRD
IMGT
MGI ID MGI:88589
MGI Symbol Cyp1a2
EMBL BC018298 BC054827 CH466522 FJ392393 K02589 M10022 M25624 X00479 X01682 X04283
GenPept AAA37508 AAA37509 AAA39873 AAH18298 AAH54827 ACJ12937 CAA25156 CAA25837 CAA27832 EDL25920
RNA Seq Atlas 13077