Version 5.4
Homo sapiens Gene: ZNF74
Summary
InnateDB Gene IDBG-1721.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF74
Gene Name zinc finger protein 74
Synonyms COS52; hZNF7; ZFP520; ZNF520
Species Homo sapiens
Ensembl Gene ENSG00000185252
Encoded Proteins
IDBP-1723
zinc finger protein 74
IDBP-1725
zinc finger protein 74
IDBP-228216
zinc finger protein 74
IDBP-292591
zinc finger protein 74
IDBP-292595
zinc finger protein 74
IDBP-363139
zinc finger protein 74
IDBP-363169
zinc finger protein 74
IDBP-812307
zinc finger protein 74
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20394115-20408461
Strand Forward strand
Band q11.21
Transcripts
ENST00000357502 ENSP00000350101
ENST00000356671 ENSP00000349098
ENST00000400451 ENSP00000383301
ENST00000405993 ENSP00000385855
ENST00000403682 ENSP00000384750
ENST00000420626 ENSP00000397011
ENST00000437275 ENSP00000395437
ENST00000493734
ENST00000476678
ENST00000611540 ENSP00000483077
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003723 RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0015629 actin cytoskeleton
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8WDT0
UniProt Splice Variant
Entrez Gene 7625
UniGene Hs.517418
RefSeq NM_001256523 NM_001256524 NM_001256525 NM_003426
HUGO HGNC:13144
OMIM 194548
CCDS CCDS42982 CCDS58794
HPRD 01928
IMGT
EMBL AC007731
GenPept
RNA Seq Atlas 7625

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca