Version 5.4
Mus musculus Gene: Nptn
Summary
InnateDB Gene IDBG-172134.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nptn
Gene Name neuroplastin
Synonyms AW554172; Sdfr1; SDR-1
Species Mus musculus
Ensembl Gene ENSMUSG00000032336
Encoded Proteins
IDBP-172140
neuroplastin
IDBP-252436
neuroplastin
IDBP-742593
IDBP-741829
IDBP-742560
IDBP-742644
IDBP-742658
IDBP-742634
IDBP-742200
IDBP-742650
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156642:
This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:58582240-58657955
Strand Forward strand
Band B
Transcripts
ENSMUST00000085651 ENSMUSP00000082793
ENSMUST00000114121 ENSMUSP00000109756
ENSMUST00000176126
ENSMUST00000175945 ENSMUSP00000135576
ENSMUST00000176896 ENSMUSP00000134761
ENSMUST00000177380 ENSMUSP00000135886
ENSMUST00000176557 ENSMUSP00000135541
ENSMUST00000176250 ENSMUSP00000135250
ENSMUST00000177292 ENSMUSP00000135199
ENSMUST00000176916 ENSMUSP00000134977
ENSMUST00000177021
ENSMUST00000177064 ENSMUSP00000135316
ENSMUST00000177020
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005105 type 1 fibroblast growth factor receptor binding
GO:0005515 protein binding
GO:0050839 cell adhesion molecule binding
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0007156 homophilic cell adhesion
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0010976 positive regulation of neuron projection development
GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0060291 long-term synaptic potentiation
Cellular Component
GO:0016021 integral component of membrane
GO:0042734 presynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000156642
View Gene Order
ENSBTAG00000008218
Not yet available
Cross-References
SwissProt P97300
TrEMBL
UniProt Splice Variant
Entrez Gene 20320
UniGene Mm.15125 Mm.408390 Mm.483298 Mm.486714
RefSeq XM_006510885 XM_006510886 NM_009145 XM_006510884 XM_006510887
OMIM
CCDS CCDS23245
HPRD
IMGT
MGI ID MGI:108077
MGI Symbol Nptn
EMBL AK075610 AK076624 AK153930 CT030640 D50463
GenPept BAA09054 BAC35855 BAC36420 BAE32261
RNA Seq Atlas 20320

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca