Version 5.4
Mus musculus Gene: Farsb
Summary
InnateDB Gene IDBG-172360.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Farsb
Gene Name phenylalanyl-tRNA synthetase, beta subunit
Synonyms C76708; Farsa; Farsl; Farslb; Frsb
Species Mus musculus
Ensembl Gene ENSMUSG00000026245
Encoded Proteins
IDBP-172364
phenylalanyl-tRNA synthetase, beta subunit
IDBP-626293
phenylalanyl-tRNA synthetase, beta subunit
IDBP-788777
phenylalanyl-tRNA synthetase, beta subunit
IDBP-788779
phenylalanyl-tRNA synthetase, beta subunit
IDBP-788780
phenylalanyl-tRNA synthetase, beta subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116120:
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:78417975-78488897
Strand Reverse strand
Band C4
Transcripts
ENSMUST00000068333 ENSMUSP00000069508
ENSMUST00000170217 ENSMUSP00000129828
ENSMUST00000189529 ENSMUSP00000140001
ENSMUST00000188247 ENSMUSP00000139933
ENSMUST00000189931
ENSMUST00000190441 ENSMUSP00000140934
ENSMUST00000191021
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0003723 RNA binding
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006432 phenylalanyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116120
View Gene Order
ENSBTAG00000011649
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00970
Aminoacyl-tRNA biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15306
Cytosolic tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
KEGG
hsa00970
Aminoacyl-tRNA biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 23874
UniGene
RefSeq NM_001278075 NM_011811
OMIM
CCDS CCDS15084
HPRD
IMGT
MGI ID MGI:1346035
MGI Symbol Farsb
EMBL
GenPept
RNA Seq Atlas 23874

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca