InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Zcchc11

Summary

InnateDB Gene

IDBG-172864.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zcchc11

Gene Name

zinc finger, CCHC domain containing 11

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000034610

Encoded Proteins

IDBP-172866

zinc finger, CCHC domain containing 11

IDBP-172868

zinc finger, CCHC domain containing 11

IDBP-268280

zinc finger, CCHC domain containing 11

IDBP-533801

zinc finger, CCHC domain containing 11

IDBP-535715

zinc finger, CCHC domain containing 11

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134744:
ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009 [PubMed 19701194]).[supplied by OMIM, Jan 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:108459426-108559421

Strand

Forward strand

Band

Transcripts

ENSMUST00000043368	ENSMUSP00000044836
ENSMUST00000097925	ENSMUSP00000095538
ENSMUST00000106673	ENSMUSP00000102284
ENSMUST00000155068	ENSMUSP00000120172
ENSMUST00000138809
ENSMUST00000151349
ENSMUST00000153916
ENSMUST00000138088
ENSMUST00000127602
ENSMUST00000145590
ENSMUST00000128042	ENSMUSP00000116253

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016779	nucleotidyltransferase activity
GO:0044822	poly(A) RNA binding
GO:0050265	RNA uridylyltransferase activity

Biological Process

GO:0001816	cytokine production
GO:0008152	metabolic process
GO:0010586	miRNA metabolic process
GO:0010587	miRNA catabolic process
GO:0019827	stem cell maintenance
GO:0031054	pre-miRNA processing
GO:0031123	RNA 3'-end processing
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0032755	positive regulation of interleukin-6 production
GO:0070102	interleukin-6-mediated signaling pathway

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000134744

View Gene Order

ENSBTAG00000002721

Not yet available

Cross-References

SwissProt

B2RX14

TrEMBL

A2A8R1 A2A9H0 Q8BIZ5 Q9EQN6

UniProt Splice Variant

Entrez Gene

230594

UniGene

Mm.25181 Mm.416791

RefSeq

NM_175472 XM_006502982 XM_006502978 XM_006502979 XM_006502980 XM_006502983 XM_006502984

OMIM

CCDS

CCDS18451

HPRD

IMGT

MGI ID

MGI:2445126

MGI Symbol

Zcchc11

EMBL

AF194972 AK049279 AK134388 AK220327 AL626783 AL627238 BC150791

GenPept

AAG38482 AAI50792 BAC33655 BAD90397 BAE22125 CAM23506 CAM25329

RNA Seq Atlas

230594