Version 5.4
Mus musculus Gene: Mrps21
Summary
InnateDB Gene IDBG-173909.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrps21
Gene Name mitochondrial ribosomal protein S21
Synonyms 1810031B19Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000054312
Encoded Proteins
IDBP-623689
mitochondrial ribosomal protein S21
IDBP-173911
mitochondrial ribosomal protein S21
IDBP-533444
mitochondrial ribosomal protein S21
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:95862634-95871519
Strand Reverse strand
Band F2.1
Transcripts
ENSMUST00000072587 ENSMUSP00000130403
ENSMUST00000067298 ENSMUSP00000066990
ENSMUST00000132515
ENSMUST00000142437 ENSMUSP00000117821
ENSMUST00000144214
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0008150 biological_process
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005840 ribosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000024378
Not yet available
Pathways
NETPATH
REACTOME
REACT_268789
Mitochondrial translation pathway
REACT_224594
Organelle biogenesis and maintenance pathway
REACT_270125
Mitochondrial translation elongation pathway
REACT_271096
Mitochondrial translation initiation pathway
REACT_270158
Mitochondrial translation termination pathway
KEGG
mmu03010
Ribosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_270797
Mitochondrial translation initiation pathway
REACT_271447
Mitochondrial translation elongation pathway
REACT_270450
Mitochondrial translation pathway
REACT_270960
Mitochondrial translation termination pathway
REACT_219259
Organelle biogenesis and maintenance pathway
KEGG
hsa03010
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt P58059
TrEMBL D3YVZ9 Q059G7
UniProt Splice Variant
Entrez Gene 66292
UniGene Mm.379108 Mm.479304
RefSeq NM_078479 XM_006525198 XM_006543354 XM_006501879
OMIM
CCDS CCDS38550
HPRD
IMGT
MGI ID MGI:1913542
MGI Symbol Mrps21
EMBL AB049956 AC092855 AC093317 AK002588 AK003462 AK003602 AK007662 AK007838 AK008265 AK008293 AK009049 AK009703 BC027546 BC125658 BC125660 CH466620
GenPept AAH27546 AAI25659 AAI25661 BAB41009 BAC24999 BAC25036 BAC25044 BAC25181 BAC25189 BAC25210 BAC25213 BAC25237 BAC25267 EDL38842 EDL38843 EDL38844
RNA Seq Atlas 102639811 66292

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca