InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Adssl1

Summary

InnateDB Gene

IDBG-174517.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adssl1

Gene Name

adenylosuccinate synthetase like 1

Synonyms

Adss; Adss1; AI528595

Species

Mus musculus

Ensembl Gene

ENSMUSG00000011148

Encoded Proteins

IDBP-174519

adenylosuccinate synthetase like 1

IDBP-712712

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185100:
ADSSL1 is a muscle isozyme of adenylosuccinate synthase (EC 6.3.4.4), which catalyzes the initial reaction in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP) (Sun et al., 2005 [PubMed 15786719]).[supplied by OMIM, Dec 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:112620045-112641354

Strand

Forward strand

Band

Transcripts

ENSMUST00000021726	ENSMUSP00000021726
ENSMUST00000180015	ENSMUSP00000136572

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0003924	GTPase activity
GO:0004019	adenylosuccinate synthase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0042803	protein homodimerization activity
GO:0051015	actin filament binding

Biological Process

GO:0006163	purine nucleotide metabolic process
GO:0006164	purine nucleotide biosynthetic process
GO:0006167	AMP biosynthetic process
GO:0006184	GTP catabolic process
GO:0006531	aspartate metabolic process
GO:0006541	glutamine metabolic process
GO:0009168	purine ribonucleoside monophosphate biosynthetic process
GO:0014850	response to muscle activity
GO:0035690	cellular response to drug
GO:0042594	response to starvation
GO:0044208	'de novo' AMP biosynthetic process
GO:0046040	IMP metabolic process
GO:0071257	cellular response to electrical stimulus