Version 5.4
| Mus musculus Gene: Adam2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-174827.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Adam2 | ||||||||
| Gene Name | a disintegrin and metallopeptidase domain 2 | ||||||||
| Synonyms | AI323749; Ftnb; Ph30-beta | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000022039 | ||||||||
| Encoded Proteins |
a disintegrin and metallopeptidase domain 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104755:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. [provided by RefSeq, Jul 2008] This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 14:66027329-66077733 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | D1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Fertilization pathway
Reproduction pathway
Interaction With The Zona Pellucida pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Interaction With The Zona Pellucida pathway
Fertilization pathway
Reproduction pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Alpha9 beta1 integrin signaling events
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| Cross-References | |||||||||
| SwissProt | Q60718 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 11495 | ||||||||
| UniGene | Mm.422850 | ||||||||
| RefSeq | NM_009618 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS36959 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1340894 | ||||||||
| MGI Symbol | Adam2 | ||||||||
| EMBL | AK016550 U16242 U22057 U38806 | ||||||||
| GenPept | AAA74921 AAA90980 AAD04207 BAB30298 | ||||||||
| RNA Seq Atlas | 11495 | ||||||||