Version 5.4
Mus musculus Gene: Mrap
Summary
InnateDB Gene IDBG-174947.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mrap
Gene Name melanocortin 2 receptor accessory protein
Synonyms 1110025G12Rik; Falp; ORF61
Species Mus musculus
Ensembl Gene ENSMUSG00000039956
Encoded Proteins
IDBP-174949
melanocortin 2 receptor accessory protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170262:
This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:90738324-90749785
Strand Forward strand
Band C3.3
Transcripts
ENSMUST00000038197 ENSMUSP00000043890
ENSMUST00000138984
ENSMUST00000125429
ENSMUST00000133973
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0031780 corticotropin hormone receptor binding
GO:0031781 type 3 melanocortin receptor binding
GO:0031782 type 4 melanocortin receptor binding
GO:0031783 type 5 melanocortin receptor binding
GO:0070996 type 1 melanocortin receptor binding
Biological Process
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0034394 protein localization to cell surface
GO:0050873 brown fat cell differentiation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000170262
View Gene Order
ENSBTAG00000023718
Not yet available
Cross-References
SwissProt Q9D159
TrEMBL
UniProt Splice Variant
Entrez Gene 77037
UniGene Mm.22455
RefSeq NM_029844
OMIM
CCDS CCDS28317
HPRD
IMGT
MGI ID MGI:1924287
MGI Symbol Mrap
EMBL AK003912 AK158113 AY079153 AY079154 BC027543
GenPept AAH27543 AAL80043 AAL80044 BAB23071 BAE34361
RNA Seq Atlas 77037

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca