Version 5.4
Mus musculus Gene: Plekhf1
Summary
InnateDB Gene IDBG-175598.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plekhf1
Gene Name pleckstrin homology domain containing, family F (with FYVE domain) member 1
Synonyms 1810013P09Rik; APPD; LAPF; PHAFIN1; ZFYVE15
Species Mus musculus
Ensembl Gene ENSMUSG00000074170
Encoded Proteins
IDBP-175600
pleckstrin homology domain containing, family F (with FYVE domain) member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166289:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:38220654-38227994
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000098513 ENSMUSP00000096113
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0046872 metal ion binding
GO:0070273 phosphatidylinositol-4-phosphate binding
Biological Process
GO:0006915 apoptotic process
GO:0007032 endosome organization
GO:0010508 positive regulation of autophagy
GO:0016050 vesicle organization
GO:0046902 regulation of mitochondrial membrane permeability
GO:0072659 protein localization to plasma membrane
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005768 endosome
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166289
View Gene Order
ENSBTAG00000008625
Not yet available
Cross-References
SwissProt Q3TB82
TrEMBL
UniProt Splice Variant
Entrez Gene 72287
UniGene Mm.333798
RefSeq NM_024413
OMIM
CCDS CCDS21158
HPRD
IMGT
MGI ID MGI:1919537
MGI Symbol Plekhf1
EMBL AK143976 AK157990 AK170283 AK171398 BC002120
GenPept AAH02120 BAE25641 BAE34303 BAE41685 BAE42432
RNA Seq Atlas 72287

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca