Version 5.4
Mus musculus Gene: Nxt2
Summary
InnateDB Gene IDBG-176131.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nxt2
Gene Name nuclear transport factor 2-like export factor 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000042271
Encoded Proteins
IDBP-176133
nuclear transport factor 2-like export factor 2
IDBP-254973
nuclear transport factor 2-like export factor 2
IDBP-254975
nuclear transport factor 2-like export factor 2
IDBP-254977
nuclear transport factor 2-like export factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101888:
The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome X:142226770-142239692
Strand Forward strand
Band F2
Transcripts
ENSMUST00000042329 ENSMUSP00000048221
ENSMUST00000112916 ENSMUSP00000108538
ENSMUST00000112914 ENSMUSP00000108536
ENSMUST00000112913 ENSMUSP00000108535
ENSMUST00000138877
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0008150 biological_process
GO:0015031 protein transport
GO:0051028 mRNA transport
Cellular Component
GO:0005575 cellular_component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101888
View Gene Order
ENSBTAG00000020739
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03013
RNA transport pathway
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q3UNA4
TrEMBL
UniProt Splice Variant
Entrez Gene 237082
UniGene Mm.41899
RefSeq NM_001161430 NM_001290532 NM_001290533 NM_172782 XM_006528798 XM_006528799
OMIM
CCDS CCDS41155 CCDS72440 CCDS72441
HPRD
IMGT
MGI ID MGI:2147914
MGI Symbol Nxt2
EMBL AK032102 AK144349 AL731672 BC068166 BC094570 BC118503 CH466610
GenPept AAH68166 AAH94570 AAI18504 BAC27701 BAE25843 CAM15877 CAM15878 CAM15879 EDL14753 EDL14754
RNA Seq Atlas 237082

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca