Version 5.4
Mus musculus Gene: Cyp4a14
Summary
InnateDB Gene IDBG-176149.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cyp4a14
Gene Name cytochrome P450, family 4, subfamily a, polypeptide 14
Synonyms AI314743
Species Mus musculus
Ensembl Gene ENSMUSG00000028715
Encoded Proteins
IDBP-176151
cytochrome P450, family 4, subfamily a, polypeptide 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:115486200-115496142
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000030487 ENSMUSP00000030487
ENSMUST00000124412
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005504 fatty acid binding
GO:0005506 iron ion binding
GO:0008391 arachidonic acid monooxygenase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0018685 alkane 1-monooxygenase activity
GO:0020037 heme binding
GO:0050544 arachidonic acid binding
GO:0052869 arachidonic acid omega-hydroxylase activity
Biological Process
GO:0001822 kidney development
GO:0009725 response to hormone
GO:0042493 response to drug
GO:0043651 linoleic acid metabolic process
GO:0046456 icosanoid biosynthetic process
GO:0048252 lauric acid metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0043231 intracellular membrane-bounded organelle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_232159
Cytochrome P450 - arranged by substrate type pathway
REACT_249802
Phase 1 - Functionalization of compounds pathway
REACT_256522
Fatty acid, triacylglycerol, and ketone body metabolism pathway
REACT_188937
Metabolism pathway
REACT_196572
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_257219
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
REACT_237452
Fatty acids pathway
REACT_198602
PPARA activates gene expression pathway
REACT_232343
Biological oxidations pathway
REACT_188625
Arachidonic acid metabolism pathway
KEGG
mmu00830
Retinol metabolism pathway
mmu00590
Arachidonic acid metabolism pathway
mmu03320
PPAR signaling pathway pathway
mmu00071
Fatty acid degradation pathway
mmu04270
Vascular smooth muscle contraction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.250901
RefSeq NM_007822
OMIM
CCDS CCDS18491
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca