Version 5.4
Mus musculus Gene: Polr3c
Summary
InnateDB Gene IDBG-176295.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Polr3c
Gene Name polymerase (RNA) III (DNA directed) polypeptide C
Synonyms 4933407E01Rik; RPC3; RPC62
Species Mus musculus
Ensembl Gene ENSMUSG00000028099
Encoded Proteins
IDBP-176297
polymerase (RNA) III (DNA directed) polypeptide C
IDBP-538761
polymerase (RNA) III (DNA directed) polypeptide C
IDBP-532369
polymerase (RNA) III (DNA directed) polypeptide C
IDBP-542523
polymerase (RNA) III (DNA directed) polypeptide C
IDBP-538979
polymerase (RNA) III (DNA directed) polypeptide C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186141:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:96711490-96727628
Strand Reverse strand
Band F2.1
Transcripts
ENSMUST00000029741 ENSMUSP00000029741
ENSMUST00000154679 ENSMUSP00000122435
ENSMUST00000128918 ENSMUSP00000119236
ENSMUST00000137009
ENSMUST00000141377 ENSMUSP00000115300
ENSMUST00000125183 ENSMUSP00000123513
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed RNA polymerase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006383 transcription from RNA polymerase III promoter
GO:0032728 positive regulation of interferon-beta production
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0051607 defense response to virus
Cellular Component
GO:0005634 nucleus
GO:0005666 DNA-directed RNA polymerase III complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186141
View Gene Order
ENSBTAG00000021637
Not yet available
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_233104
RNA Polymerase III Transcription Initiation pathway
REACT_250309
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_230745
Immune System pathway
REACT_251592
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_261233
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_218897
Cytosolic sensors of pathogen-associated DNA pathway
REACT_233572
Gene Expression pathway
REACT_221403
RNA Polymerase III Transcription Termination pathway
REACT_237241
RNA Polymerase III Transcription pathway
REACT_240508
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_205207
RNA Polymerase III Chain Elongation pathway
KEGG
mmu00240
Pyrimidine metabolism pathway
mmu03020
RNA polymerase pathway
mmu00230
Purine metabolism pathway
mmu04623
Cytosolic DNA-sensing pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_63
RNA Polymerase III Transcription Termination pathway
REACT_756
RNA Polymerase III Chain Elongation pathway
REACT_571
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_1036
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
REACT_347
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_118823
Cytosolic sensors of pathogen-associated DNA pathway
REACT_71
Gene Expression pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
hsa03020
RNA polymerase pathway
hsa04623
Cytosolic DNA-sensing pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q9D483
TrEMBL B2RX77
UniProt Splice Variant
Entrez Gene 74414
UniGene Mm.276043 Mm.404180
RefSeq XM_006502187 XM_006502188 NM_028925
OMIM
CCDS CCDS51010
HPRD
IMGT
MGI ID MGI:1921664
MGI Symbol Polr3c
EMBL AK016716 BC026793 BC147485 BC151028 CH466620
GenPept AAH26793 AAI47486 AAI51029 BAB30395 EDL38917
RNA Seq Atlas 74414

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca