InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Mrpl22

Summary

InnateDB Gene

IDBG-176304.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mrpl22

Gene Name

mitochondrial ribosomal protein L22

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020514

Encoded Proteins

IDBP-176306

mitochondrial ribosomal protein L22

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000082515:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:58171661-58179565

Strand

Forward strand

Band

B1.3

Transcripts

ENSMUST00000020820	ENSMUSP00000020820
ENSMUST00000133038
ENSMUST00000140997

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.