Version 5.4
| Mus musculus Gene: Dhps | |||||||||||||||||
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| Summary | |||||||||||||||||
| InnateDB Gene | IDBG-176552.6 | ||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
| Gene Symbol | Dhps | ||||||||||||||||
| Gene Name | deoxyhypusine synthase | ||||||||||||||||
| Synonyms | |||||||||||||||||
| Species | Mus musculus | ||||||||||||||||
| Ensembl Gene | ENSMUSG00000060038 | ||||||||||||||||
| Encoded Proteins |
deoxyhypusine synthase
deoxyhypusine synthase
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| Protein Structure | |||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
| Entrez Gene | |||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095059:
This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011] |
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| Gene Information | |||||||||||||||||
| Type | Protein coding | ||||||||||||||||
| Genomic Location | Chromosome 8:85071757-85075162 | ||||||||||||||||
| Strand | Forward strand | ||||||||||||||||
| Band | C3 | ||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
Metabolism of proteins pathway
Post-translational protein modification pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
Hypusine synthesis from eIF5A-lysine pathway
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| KEGG | |||||||||||||||||
| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||
| NETPATH | |||||||||||||||||
| REACTOME |
Hypusine synthesis from eIF5A-lysine pathway
Post-translational protein modification pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
Metabolism of proteins pathway
Hypusine synthesis from eIF5A-lysine pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
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| KEGG | |||||||||||||||||
| INOH | |||||||||||||||||
| PID NCI | |||||||||||||||||
| Cross-References | |||||||||||||||||
| SwissProt | |||||||||||||||||
| TrEMBL | |||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||
| Entrez Gene | |||||||||||||||||
| UniGene | Mm.193086 | ||||||||||||||||
| RefSeq | NM_001039514 XM_006531131 | ||||||||||||||||
| OMIM | |||||||||||||||||
| CCDS | CCDS22492 | ||||||||||||||||
| HPRD | |||||||||||||||||
| IMGT | |||||||||||||||||
| MGI ID | |||||||||||||||||
| MGI Symbol | |||||||||||||||||
| EMBL | |||||||||||||||||
| GenPept | |||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||