Mus musculus Gene: Lim2
Summary
InnateDB Gene IDBG-176792.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lim2
Gene Name lens intrinsic membrane protein 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000004613
Encoded Proteins
lens intrinsic membrane protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105370:
This gene encodes an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:43430088-43435991
Strand Forward strand
Band B3
Transcripts
ENSMUST00000004732 ENSMUSP00000004732
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005212 structural constituent of eye lens
Biological Process
GO:0002088 lens development in camera-type eye
GO:0043010 camera-type eye development
Cellular Component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
GO:0031982 vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt P56563
TrEMBL
UniProt Splice Variant
Entrez Gene 233187
UniGene
RefSeq NM_177693 XM_006540818
OMIM
CCDS CCDS21168
HPRD
IMGT
MGI ID MGI:104698
MGI Symbol Lim2
EMBL AF320075 AK029354 AK164958 BC119253 BC119255
GenPept AAI19254 AAI19256 AAK08062 BAC26414 BAE37979
RNA Seq Atlas 233187