Version 5.4
Mus musculus Gene: Atp5o
Summary
InnateDB Gene IDBG-177431.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp5o
Gene Name ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
Synonyms ATPO; D12Wsu28e; OSCP
Species Mus musculus
Ensembl Gene ENSMUSG00000022956
Encoded Proteins
IDBP-177433
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
IDBP-537122
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
IDBP-539465
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000241837:
The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:91684398-91931687
Strand Reverse strand
Band C4
Transcripts
ENSMUST00000023677 ENSMUSP00000023677
ENSMUST00000159295 ENSMUSP00000125172
ENSMUST00000150642
ENSMUST00000155452 ENSMUSP00000118216
ENSMUST00000139277
ENSMUST00000154661
ENSMUST00000132049
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005496 steroid binding
GO:0032403 protein complex binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0015986 ATP synthesis coupled proton transport
GO:0046034 ATP metabolic process
Cellular Component
GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0005739 mitochondrion
GO:0005753 mitochondrial proton-transporting ATP synthase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000241837
View Gene Order
ENSBTAG00000018278
Not yet available
Pathways
NETPATH
REACTOME
REACT_189162
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_188937
Metabolism pathway
REACT_261922
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_245290
Formation of ATP by chemiosmotic coupling pathway
KEGG
mmu00190
Oxidative phosphorylation pathway
mmu05010
Alzheimer's disease pathway
mmu05012
Parkinson's disease pathway
mmu05016
Huntington's disease pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_6759
Formation of ATP by chemiosmotic coupling pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
REACT_212639
Formation of ATP by chemiosmotic coupling pathway
REACT_215469
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_218878
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_219139
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_138597 XM_006543757
OMIM
CCDS CCDS28331
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca