Version 5.4
Mus musculus Gene: Mob1b
Summary
InnateDB Gene IDBG-177562.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mob1b
Gene Name MOB kinase activator 1B
Synonyms 1110003E08Rik; AU015450; B230364F10; Mobkl1a
Species Mus musculus
Ensembl Gene ENSMUSG00000006262
Encoded Proteins
IDBP-177564
MOB kinase activator 1B
IDBP-254333
MOB kinase activator 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173542:
The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:88720855-88762058
Strand Forward strand
Band E1
Transcripts
ENSMUST00000006424 ENSMUSP00000006424
ENSMUST00000113229 ENSMUSP00000108855
ENSMUST00000155298
ENSMUST00000125171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019209 kinase activator activity
GO:0019900 kinase binding
GO:0046872 metal ion binding
Biological Process
GO:0035329 hippo signaling
GO:0042327 positive regulation of phosphorylation
GO:0046777 protein autophosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000173542
View Gene Order
ENSBTAG00000016290
Not yet available
Pathways
NETPATH
REACTOME
REACT_196537
Signaling by Hippo pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118607
Signaling by Hippo pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BPB0
TrEMBL Q3T9U1 Q3UDM0
UniProt Splice Variant
Entrez Gene 68473
UniGene Mm.35764 Mm.409031 Mm.419728
RefSeq NM_026735
OMIM
CCDS CCDS39139
HPRD
IMGT
MGI ID MGI:1915723
MGI Symbol Mob1b
EMBL AC160533 AK077320 AK150016 AK162120 AK172291 BC104402 BC104403 CH466617
GenPept AAI04403 AAI04404 BAC36748 BAE29241 BAE36736 BAE42929 EDL05348
RNA Seq Atlas 68473

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca