Mus musculus Gene: H2-D1
Summary
InnateDB Gene IDBG-177614.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2-D1
Gene Name histocompatibility 2, D region locus 1
Synonyms H-2D; H-2L; H2-D
Species Mus musculus
Ensembl Gene ENSMUSG00000073411
Encoded Proteins
histocompatibility 2, D region locus 1
histocompatibility 2, D region locus 1
histocompatibility 2, D region locus 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35262730-35267499
Strand Forward strand
Band B1
Transcripts
ENSMUST00000172785 ENSMUSP00000134570
ENSMUST00000174325
ENSMUST00000173167 ENSMUSP00000133518
ENSMUST00000172503 ENSMUSP00000134582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Class I MHC mediated antigen processing & presentation pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Cytokine Signaling in Immune system pathway
Immune System pathway
ER-Phagosome pathway pathway
Endosomal/Vacuolar pathway pathway
Interferon gamma signaling pathway
Interferon Signaling pathway
Antigen processing-Cross presentation pathway
Adaptive Immune System pathway
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
KEGG
Cell adhesion molecules (CAMs) pathway
Type I diabetes mellitus pathway
Antigen processing and presentation pathway
Natural killer cell mediated cytotoxicity pathway
Allograft rejection pathway
Graft-versus-host disease pathway
Autoimmune thyroid disease pathway
Endocytosis pathway
Viral myocarditis pathway
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001267808 NM_010380 XM_006544803
OMIM
CCDS CCDS57074
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas