Mus musculus Gene: Gigyf2 | |||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||
InnateDB Gene | IDBG-178126.6 | ||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||
Gene Symbol | Gigyf2 | ||||||||||||||||||||||||
Gene Name | GRB10 interacting GYF protein 2 | ||||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000048000 | ||||||||||||||||||||||||
Encoded Proteins |
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
GRB10 interacting GYF protein 2
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Protein Structure | |||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204120:
The protein encoded by this gene interacts with GRB10 and may be involved in the regulation of tyrosine kinase receptor signaling. This gene contains CAG repeats, and the encoded protein contains stretches glutamine and glutamic acid residues. Defects in this gene are a cause of Parkinson disease type 11 (PARK11). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
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Gene Information | |||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||
Genomic Location | Chromosome 1:87326998-87450796 | ||||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||||
Band | C5 | ||||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||||
Interactions | |||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
UniGene | Mm.23065 Mm.412415 Mm.413309 | ||||||||||||||||||||||||
RefSeq | NM_001110212 NM_146112 XM_006529464 XM_006529465 XM_006529466 XM_006529467 XM_006529470 | ||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||
CCDS | CCDS15133 CCDS56636 | ||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||||
EMBL | |||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||||