Version 5.4
Mus musculus Gene: Cbln1
Summary
InnateDB Gene IDBG-178238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cbln1
Gene Name cerebellin 1 precursor protein
Synonyms AI323299
Species Mus musculus
Ensembl Gene ENSMUSG00000031654
Encoded Proteins
IDBP-178240
cerebellin 1 precursor protein
IDBP-621299
cerebellin 1 precursor protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102924:
This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:87468854-87472592
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000034076 ENSMUSP00000034076
ENSMUST00000169693 ENSMUSP00000126575
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007157 heterophilic cell-cell adhesion
GO:0009306 protein secretion
GO:0021707 cerebellar granule cell differentiation
GO:0051965 positive regulation of synapse assembly
Cellular Component
GO:0005576 extracellular region
GO:0030054 cell junction
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000102924
View Gene Order
ENSBTAG00000015194
Not yet available
Cross-References
SwissProt Q9R171
TrEMBL Q7TNF5 Q80W16
UniProt Splice Variant
Entrez Gene 12404
UniGene Mm.470723
RefSeq NM_019626
OMIM
CCDS CCDS22506
HPRD
IMGT
MGI ID MGI:88281
MGI Symbol Cbln1
EMBL AF164680 BC051956 BC055730 BC132120 BC132122 CH466525 X61448
GenPept AAD47280 AAH51956 AAH55730 AAI32121 AAI32123 CAA43688 EDL11038
RNA Seq Atlas 12404

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca