Version 5.4
Mus musculus Gene: Dync1i2
Summary
InnateDB Gene IDBG-178613.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dync1i2
Gene Name dynein cytoplasmic 1 intermediate chain 2
Synonyms 3110079H08Rik; AW554389; Dncic2
Species Mus musculus
Ensembl Gene ENSMUSG00000027012
Encoded Proteins
IDBP-178615
dynein cytoplasmic 1 intermediate chain 2
IDBP-178617
dynein cytoplasmic 1 intermediate chain 2
IDBP-256605
dynein cytoplasmic 1 intermediate chain 2
IDBP-256607
dynein cytoplasmic 1 intermediate chain 2
IDBP-256609
dynein cytoplasmic 1 intermediate chain 2
IDBP-256611
dynein cytoplasmic 1 intermediate chain 2
IDBP-256613
dynein cytoplasmic 1 intermediate chain 2
IDBP-256615
dynein cytoplasmic 1 intermediate chain 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000077380:
This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:71211706-71263303
Strand Forward strand
Band C2
Transcripts
ENSMUST00000100028 ENSMUSP00000097605
ENSMUST00000081710 ENSMUSP00000080410
ENSMUST00000112144 ENSMUSP00000107772
ENSMUST00000112142 ENSMUSP00000107770
ENSMUST00000112140 ENSMUSP00000107768
ENSMUST00000112139 ENSMUSP00000107767
ENSMUST00000112138 ENSMUSP00000107766
ENSMUST00000112136 ENSMUSP00000107764
ENSMUST00000141619
ENSMUST00000149735
ENSMUST00000137683
ENSMUST00000138613
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005813 centrosome
GO:0005868 cytoplasmic dynein complex
GO:0005874 microtubule
GO:0031982 vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000077380
View Gene Order
ENSBTAG00000002646
Not yet available
Pathways
NETPATH
REACTOME
REACT_245720
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_240530
G2/M Transition pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_243078
Loss of Nlp from mitotic centrosomes pathway
REACT_188804
Cell Cycle pathway
REACT_230745
Immune System pathway
REACT_246508
Mitotic G2-G2/M phases pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_244487
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_196635
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_229531
Adaptive Immune System pathway
REACT_253753
Centrosome maturation pathway
KEGG
mmu04962
Vasopressin-regulated water reabsorption pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160315
Regulation of PLK1 Activity at G2/M Transition pathway
REACT_15364
Loss of Nlp from mitotic centrosomes pathway
REACT_15451
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
REACT_15296
Recruitment of mitotic centrosome proteins and complexes pathway
REACT_121399
MHC class II antigen presentation pathway
REACT_115566
Cell Cycle pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_15479
Centrosome maturation pathway
REACT_2203
G2/M Transition pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_21391
Mitotic G2-G2/M phases pathway
KEGG
hsa04962
Vasopressin-regulated water reabsorption pathway
hsa04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A2BFF8
UniProt Splice Variant
Entrez Gene 13427
UniGene Mm.249479 Mm.431557 Mm.462387
RefSeq NM_001198872 NM_001198873 NM_001198874 NM_001198875 NM_001198876 NM_001198877 NM_001198878 NM_010064 XM_006498674 XM_006498675 XM_006498676 XM_006498677 XM_006498678 XM_006498679 XM_006498681
OMIM
CCDS CCDS16112 CCDS57175
HPRD
IMGT
MGI ID MGI:107750
MGI Symbol Dync1i2
EMBL BX284624 BX544878
GenPept
RNA Seq Atlas 13427

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca